Large home on desirable, tree-lined University City block in the Penn Alexander School Catchment. Significant home with superb bones. Needs a complete renovation. 6 bedrooms, family room, 3 full baths. Substantial character including high ceilings, leaded glass, original floors, original staircase, original doors, lincrusta wainscoting, three originals mantles, and more. Large rear yard. Ample closets and storage. Substantial space throughout. A+ location in the Penn Alexander Catchment. Within blocks of Clark Park and its superb Farmers' Market, ReAnimator and Earth Cup Coffee, Local 44, Bottle Shop, Green Line Cafe, Taco Taco (formerly Honest Tom's), Tampopo, Don Barriga, Pop Shop, Milk and Honey, Renata's, Clarkville, Baltimore Avenue Restaurant Row, CVS, and much more. Walk to HUP, Penn, CHOP, Penn Vet, Drexel, University of the Sciences. 12 minutes to Rittenhouse Square by car and plenty of convenient SEPTA options. NOTES--this home is available separately or as a package with the adjoining twin, 501 S 45th. This home is zoned residential with a variance for three units. It is currently set up as one home and is leased to a Univ. of the Sciences fraternity for $3,000/month through May 2020. Accordingly, it is also listed as a multi-unit.